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This is the home of the CH444 - Advanced Topics in Biochemistry


Instructor: Kevin Rice (Keyes 313, x5763, kprice@colby.edu)



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CH444 Syllabus\

Weekly class assignments

CH444 message board
Final Project information
Information on writing assignments
Primary Literature / Vendor Resources


Approximate weekly lecture schedule

Week of

Lecture Topic

Reading / Textook Chapters

Assignments, etc.

2/10

Introduction / Model organisms / cell culture / cell fractionation 

Chapter 1-4

JBC review, due in class

2/17

Molecular Biology / cloning / genomics

Chapters 5-6

Literature search, due in class
JBC review, due in class
Writing assignment 1a, due by email on 2/21

2/24

Electrophoresis / chromotography / protein purification

Chapters 8, 10, 11

JBC review, due in class
Writing assignment 1b, due by email on 2/28

3/3

Enzyme assay development / enzyme mechanisms

Chapter 15

Peer review, due in class
Writing assignment 1c, due by email on 3/7

3/10

Immunological assays / radioisotope techniques

Chapters 7, 14

JBC review, due in class

3/17

Mid-term oral presentations

 

 

3/24

Spring Break

Chapters 7 & 14


3/31

Mass spectroscopy / proteomics

Chapters 9, 12, & 13

JBC review, due in class
Final project executive summary, due by email on 4/4

4/7

Modern approaches to experimental biochemistry I

TBD


4/14

Modern approaches to experimental biochemistry II

TBD

In-class examination:  4/2
Out-of-class meetings:  4/5-4/6

4/21

Modern approaches to experimental biochemistry III

TBD

Project introduction:  4/13

4/28

Modern approaches to experimental biochemistry IV

TBD

 

5/5

Final oral presentations

 

Project draft:  4/23

 

 

 

Project final submission:  5/11

Mid-term oral presentation schedule

Oral presentations will be presented in the order given below (unless folks mutually agree to switch).  Each student will choose a paper from the journal linked next to her/his name and email it Kevin by Wednesday 2/29.  The requirements are that the paper must be:  1) biochemical in scope, 2) published in 2012, 3) a full paper, not a communication or review, and 4) something about which you are really excited.  For a more complete set of expectations, click the link below.  Remember, all students will be required to evaluate the others' presentations.  You should preview the evaluation for to get further clues as to the means of assessment.

  - 

Order

Presenter

Source Journal

Presented Paper

1


Chemistry and Biology

 

2


Biochemistry


3

 

Molecular Cancer

 

4

 

Molecular Cell

 

5

 

Nucleic Acids Research

 

6

 

Molecular and Cellular Biology


7

 

ACS Chemical Biology

 







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