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This is the home of the CH444 - Advanced Topics in Biochemistry

Instructor: Kevin Rice (Keyes 313, x5763,

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Download CH444 Syllabus

Weekly class assignments

CH444 message board
Final Project information
Information on writing assignments

Approximate weekly lecture schedule

Week of

Lecture Topic

Reading / Textook Chapters


Introduction / primary literature

Chapter 1


Model organisms / cell culture / cell fractionation

Chapters 2-4


Molecular Biology / cloning / genomics

Chapters 5-6


Electrophoresis / chromotography / protein purification

Chapters 8, 10, & 11


Enzyme assay development / enzyme mechanisms

Chapter 15


Mid-term oral presentations



Immunological assays / radioisotope techniques

Chapters 7 & 14


Spring Break



Mass spectroscopy / proteomics

Chapters 9, 12, & 13


Novel approaches to experimental biochemistry I



Novel approaches to experimental biochemistry II



Novel approaches to experimental biochemistry III



Novel approaches to experimental biochemistry IV



Final oral presentations


Mid-term oral presentation schedule

Oral presentations will be presented in the order given below (unless folks mutually agree to switch).  Each student will choose a paper from the journal linked next to her/his name and email it Kevin by Wednesday 3/2.  The requirements are that the paper must be:  1) biochemical in scope, 2) published in 2011, 3) a full paper, not a communication or review, and 4) something about which you are really excited.  For a more complete set of expectations, click the link below.  Remember, all students will be required to evaluate the others' presentations.  You should preview the evaluation for to get further clues as to the means of assessment.

Oral presentation guidelines  -  Oral presentation evaluation form

Primary Literature Resources

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