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BC367 - Biochemistry of the Cell I

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Instructor: Kevin Rice (Keyes 313, x5763, kprice@colby.edu)

 

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Download BC362 Syllabus

Weekly class assignments

Laboratory

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BC367 syllabus

BC367 message board

Examinations

Kevin's Calendar

 

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BC367 Learning Goals

  1. To learn the fundamental chemistry and biochemistry of major classes of biomolecules, including amino acids and proteins, sugars and polysaccharides, nucleotides and nucleic acids, and lipids.
  2. To understand how chemical reactivity, thermodynamics, and kinetics are responsible for life.
  3. To sharpen problem-solving skills of both a qualitative and quantitative nature and to solve problems that involve the integration and synthesis of new knowledge.
  4. To enhance written and oral communication skills and build confidence in oral expression in a group setting.

 

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Approximate Lecture and Discussion Schedule

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Week of:

Probable topic:

Textbook chapter(s):

Discussion topic (guest)materials:

29/3

Chemical equilibria and thermodynamic

1-4

Preparing for and applying to health professional school
(Cate Talbot Ashton, Colby Career Center)

2/8

Amino acids and peptides

5

"Acute aspirin overdose, a case study"

2/15

Protein structure

5

"Protein Homology Searching, a case study"

2/22

Protein dynamics

5

"How do crocodiles hold their breath for so long?"

3/1

Enzyme kinetics and mechanisms

6

"Biopharmaceuticals"

3/8

Enzyme inhibition and regulation

6

Exam 1

3/15

Carbohydrates

7

Problem set discussion

3/22

             Spring break

 

 

3/29

Glycolysis

8

"Hypertension and Receptor Mutations" , with Dr. Charles Jacobs

4/5

Citric acid cycle and oxidative phosphorylation

9, 10

"A life-threatening complication of the Atkins Diet, a case study"

4/12

Lipids and membrane transport

11

Metabolic Diseases, with Dr. Mike Antoniello

4/19

Nitrogen / amino acid metabolism

14, 15

Exam 2

4/26

The "Central Dogma"

18, 19

Problem set discussion

5/3

Biological signal transduction

16

Diabetes Discussion (Read textbook, pages 606-608)

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Pre-med Resources

Chemistry Resources

6

Living matter / aqueous chemistry

1, 2

Problem Set #1

9/11

Amino acids

3

Problem Set #2

9/18

Peptides and proteins

3-4

Problem Set #3

BLAST homepage

9/25

Protein structure

3-4

Problem Set #4

10/2

Protein dynamics

5

(no problem set this week)

10/9

Enzymes and enzyme kinetics

6

Problem Set #5

10/16

Enzyme inhibition

6

Homework #6

10/23

Enzyme mechanisms

6

Homework #7

10/30

Sugars, polysaccharides, and glycobiology

7

Homework #8

11/6

Nucleotides and nucleic acid structure

8

Homework #9

11/13

Nucleic acid chemistry and function

8

(no problem set this week)

11/20

DNA technology and lipid chemistry

9-10

(no problem set this week)

11/27

Storage and structural lipids

10

Problem Set #10

12/4

Lipid biology

10

Homework #11

 

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