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This is the home of the CH444 - Advanced

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Methods in Biochemistry

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Instructor: Kevin Rice (Keyes 313,

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(207) 859-5763, kevin.rice@colby.edu)

 

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Blog Posts
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CH444 Syllabus

Kevin's Calendar

Weekly class assignments

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Class meeting schedule

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CH444 message board

Final Project information

Information on writing assignments

Primary Literature / Vendor Resources

Approximate weekly schedule, Spring 2014

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Week of

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Lecture Topic

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Reading / Textook Chapters

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Assignments, etc.

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2/9

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Introduction / Model organisms / cell culture / cell fractionation 

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Chapter 1-4

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JBC review, due in class

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2/16

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Molecular Biology / cloning / genomics

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Chapters 5-6

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Literature search, due in class
JBC review, due in class
Writing assignment 1a, due by email on 2/20

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2/23

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Electrophoresis / chromatography / protein purification

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Chapters 8, 10, 11

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JBC review, due in class
Writing assignment 1b, due by email on 2/27

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3/2

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In-class writing workshop
Enzyme assay development / enzyme mechanisms

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Chapter 15

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Peer review, due in class

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3/9

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Immunological assays / radioisotope techniques

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Chapters 7, 14

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JBC review, due in class
Writing assignment 1c, due by email on

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3/16

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Mid-term oral presentations

 

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3/23

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Spring Break

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3/30

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Mass spectroscopy / proteomics

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Chapters 9, 12, & 13

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JBC review, due in class
Final project executive summary, due by email on

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4/6

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Mid-term examination

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1-on1 meetings with Kevin

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4/13

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Modern approaches to experimental biochemistry I

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TBD

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Literature review, due in class
Final project introduction, due by email on

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4/20

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Modern approaches to experimental biochemistry II

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TBD

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Literature review, due in class
Final project draft, due by email on

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4/27

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Modern approaches to experimental biochemistry III

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TBD

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Final project peer review, due in class

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5/4

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Final oral presentations

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Final project, due by email on

Mid-term oral presentation schedule

Oral presentations will be presented in the order given below (unless folks mutually agree to switch).  Each student will choose a paper from the journal linked next to her/his name and email it to Kevin by Monday 3/9.  The requirements are that the paper must be:  1) biochemical in scope, 2) published in 2014, 3) a full paper, not a communication or review, and 4) something about which you are really excited.  Remember, all students will be required to evaluate the others' presentations.  Detailed guidelines and evaluation rubrics can be viewed here.

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Order

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Presenter

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Source Journal

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Presented Paper

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1

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Chemistry and Biology

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2

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Biochemistry

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3

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Molecular Cancer

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4

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Nucleic Acids Research

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5

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Molecular and Cellular Biology

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6

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ACS Chemical Biology

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