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This is the home of the CH444 - Advanced

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Methods in Biochemistry

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Instructor: Kevin Rice (Keyes 313,

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(207) 859-5763, kevin.rice@colby.edu)

 

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Blog Posts
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CH444 Syllabus

Kevin's Calendar

Weekly class assignments

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Class meeting schedule

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CH444 message board

Final Project information

Information on writing assignments

Primary Literature / Vendor Resources

Approximate weekly lecture schedule

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Week of

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Lecture Topic

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Reading / Textook Chapters

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Writing Assignments

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2/1

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Introduction / primary literature

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Chapter 1

 

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2/6

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Model organisms / cell culture / cell fractionation

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Chapters 2-4

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Literature search:  2/6
JBC review:  2/10

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2/13

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Molecular Biology / cloning / genomics

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Chapters 5-6

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JBC review:  2/17

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2/20

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Electrophoresis / chromotography / protein purification

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Chapters 8, 10, & 11

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Writing assignment 1:  2/20
JBC review:  2/24

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2/27

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Enzyme assay development / enzyme mechanisms

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Chapter 15

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Writing assignment 2:  2/27
Peer review: 3/2

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3/5

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Mid-term oral presentations

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3/12

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Immunological assays / radioisotope techniques

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Chapters 7 & 14

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Rewrite:  3/16

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3/19

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Spring Break

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3/26

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Mass spectroscopy / proteomics

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Chapters 9, 12, & 13

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Project executive summary:  3/30

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4/2

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Modern approaches to experimental biochemistry I

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In-class examination:  4/2
Out-of-class meetings:  4/5-4/6

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4/9

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Modern approaches to experimental biochemistry II

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Project introduction:  4/13

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4/16

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Modern approaches to experimental biochemistry III

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4/23

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Final oral presentations

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Project draft:  4/23

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4/30

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Final oral presentations

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?Project final submission:  5/11

Mid-term oral presentation schedule

Oral presentations will be presented in the order given below (unless folks mutually agree to switch).  Each student will choose a paper from the journal linked next to her/his name and email it Kevin by Wednesday 2/29.  The requirements are that the paper must be:  1) biochemical in scope, 2) published in 2012, 3) a full paper, not a communication or review, and 4) something about which you are really excited.  For a more complete set of expectations, click the link below.  Remember, all students will be required to evaluate the others' presentations.  You should preview the evaluation for to get further clues as to the means of assessment.

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Oral presentation guidelines  -  Oral presentation evaluation form

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Date

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Presenters

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Source Journal

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Presented Paper

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March 5

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Adam / Charlie

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Chemistry and Biology

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link to paper

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Christine / Abigael

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Biochemistry

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March 7

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Kayla / Rachel

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ACS Chemical Biology

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paper

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Beatrice / Jackson

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Molecular Cell

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March 9  

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Tyler

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Nucleic Acids Research

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