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This is the home of the CH444 - Advanced Topics in Biochemistry


Instructor: Kevin Rice (Keyes 313, x5763, kprice@colby.edu)



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CH444 Syllabus

Weekly class assignments

CH444 message board
Final Project information
Information on writing assignments


Approximate weekly lecture schedule

Week of

Lecture Topic

Reading / Textook Chapters

Writing Assignments

2/1

Introduction / primary literature

Chapter 1

 

2/6

Model organisms / cell culture / cell fractionation

Chapters 2-4

Literature search:  2/6
JBC review:  2/10

2/13

Molecular Biology / cloning / genomics

Chapters 5-6

JBC review:  2/17

2/20

Electrophoresis / chromotography / protein purification

Chapters 8, 10, & 11

Writing assignment 1:  2/20
JBC review:  2/24

2/27

Enzyme assay development / enzyme mechanisms

Chapter 15

Writing assignment 2:  2/27
Peer review: 3/2

3/5

Mid-term oral presentations

 

 

3/12

Immunological assays / radioisotope techniques

Chapters 7 & 14

Rewrite:  3/16

3/19

Spring Break

 

 

3/26

Mass spectroscopy / proteomics

Chapters 9, 12, & 13

Project executive summary:  3/30

4/2

Modern approaches to experimental biochemistry I

 

In-class examination:  4/2
Out-of-class meetings:  4/5-4/6

4/9

Modern approaches to experimental biochemistry II

 

Project introduction:  4/13

4/16

Modern approaches to experimental biochemistry III

 

 

4/23

Final oral presentations

 

Project draft:  4/23

4/30

Final oral presentations

 

 

 

 

 

?Project final submission:  5/11

Mid-term oral presentation schedule

Oral presentations will be presented in the order given below (unless folks mutually agree to switch).  Each student will choose a paper from the journal linked next to her/his name and email it Kevin by Wednesday 2/29.  The requirements are that the paper must be:  1) biochemical in scope, 2) published in 2012, 3) a full paper, not a communication or review, and 4) something about which you are really excited.  For a more complete set of expectations, click the link below.  Remember, all students will be required to evaluate the others' presentations.  You should preview the evaluation for to get further clues as to the means of assessment.

Oral presentation guidelines  -  Oral presentation evaluation form

Date

Presenters

Source Journal

Presented Paper

March 5

Adam / Charlie

Chemistry and Biology


 

Christine / Abigael

Biochemistry


March 7

Kayla / Rachel

ACS Chemical Biology


 

Beatrice / Jackson

Molecular Cell


March 9  

Tyler

Nucleic Acids Research


 

 







Primary Literature Resources



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