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This is the home of the CH444 - Advanced Methods in Biochemistry


Instructor: Kevin Rice (Keyes 313, x5763, kprice@colby.edu)



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CH444 Syllabus
Kevin's Calendar

Weekly class assignments

CH444 message board
Final Project information
Information on writing assignments
Primary Literature / Vendor Resources


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Approximate weekly schedule, Spring 2015

Week of

Lecture Topic

Reading / Textook Chapters

Assignments, etc.

2/9

Introduction / Model organisms / cell culture / cell fractionation 

Chapter 1-4

JBC review, due in class

2/16

Molecular Biology / cloning / genomics

Chapters 5-6

[Literature search|^LitAssignment15.pdf], due in class
JBC review, due in class
[Writing assignment 1a|^WriteAssign1a_15.pdf], due by email on 2/20

2/23

Electrophoresis / chromatography / protein purification

Chapters 8, 10, 11

JBC review, due in class
[Writing assignment 1b|^WriteAssign1b_15.pdf], due by email on 2/27

3/2

In-class writing workshop
Enzyme assay development / enzyme mechanisms

Chapter 15

[Peer review|^PeerReview_15.pdf], due in class

3/9

Immunological assays / radioisotope techniques

Chapters 7, 14

JBC review, due in class
[Writing assignment 1c|^WriteAssign1c_15.pdf], due by email on 3/11

3/16

Mid-term oral presentations

 

 

3/23

Spring Break



3/30

Mass spectroscopy / proteomics

Chapters 9, 12, & 13

JBC review, due in class
[Final project executive summary|^FinalProject_ExecSum_14.docx], due by email on 4/3

4/6

Mid-term examination


1-on1 meetings with Kevin

4/13

Modern approaches to experimental biochemistry I

TBD

Literature review, due in class
Final project introduction, due by email on

4/20

Modern approaches to experimental biochemistry II

TBD

Literature review, due in class
Final project draft, due by email on

4/27

Modern approaches to experimental biochemistry III

TBD

Final project peer review, due in class

5/4

Final oral presentations

 


 

 

 

Final project, due by email on

Mid-term oral presentation schedule

Oral presentations will be presented in the order given below (unless folks mutually agree to switch).  Each student will choose a paper from the journal linked next to her/his name and email it to Kevin by Monday 3/9.  The requirements are that the paper must be:  1) biochemical in scope, 2) published in 2015, 3) a full paper, not a communication or review, and 4) something about which you are really excited.  Remember, all students will be required to evaluate the others' presentations.  Detailed guidelines and evaluation rubrics [can be viewed here|^MidtermOral_Guidelines_15.pdf].

Order

Presenter

Source Journal

Presented Paper

1

Ryan

Chemistry and Biology

Segal, et al.

2

Darcy

Biochemistry

Ryan, et al.

3

Sam

Molecular Cancer

Tuna, et al.

4

Colin

Nucleic Acids Research

Beloglazova, et al.

5

Vania

Molecular and Cellular Biology

Sohni, et al.

6

Sarah

ACS Chemical Biology

Magpusao, et al.

7

Megan

Journal of Molecular Biology

He, et al.







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