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This is the home of the CH444 - Advanced Topics in Biochemistry


Instructor: Kevin Rice (Keyes 313, x5763, kprice@colby.edu)



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CH444 Syllabus

Weekly class assignments

CH444 message board
Final Project information
Information on writing assignments
Primary Literature / Vendor Resources


Approximate weekly lecture schedule

Week of
Lecture Topic
Reading / Textook Chapters
Assignments, etc.
2/1
Introduction / primary literature
Chapter 1
 
2/6
Model organisms / cell culture / cell fractionation
Chapters 2-4
Literature search:  2/6
JBC review:  2/10
2/13
Molecular Biology / cloning / genomics
Chapters 5-6
JBC review:  2/17
2/20
Electrophoresis / chromotography / protein purification
Chapters 8, 10, & 11
Writing assignment 1:  2/20
JBC review:  2/24
2/27
Enzyme assay development / enzyme mechanisms
Chapter 15
Writing assignment 2:  2/27
Peer review: 3/2
3/5
Mid-term oral presentations
   
3/12
Immunological assays / radioisotope techniques
Chapters 7 & 14
Writing assignment 3:  3/16
3/19
Spring Break
   
3/26
Mass spectroscopy / proteomics
Chapters 9, 12, & 13 Project executive summary:  3/30
4/2
Modern approaches to experimental biochemistry I   In-class examination:  4/2
Out-of-class meetings:  4/5-4/6
4/9
Modern approaches to experimental biochemistry II   Project introduction:  4/13
4/16
Modern approaches to experimental biochemistry III    
4/23
Final oral presentations
  Project draft:  4/23
4/30
Final oral presentations
   
      Project final submission:  5/11

Mid-term oral presentation schedule

Oral presentations will be presented in the order given below (unless folks mutually agree to switch).  Each student will choose a paper from the journal linked next to her/his name and email it Kevin by Wednesday 2/29.  The requirements are that the paper must be:  1) biochemical in scope, 2) published in 2012, 3) a full paper, not a communication or review, and 4) something about which you are really excited.  For a more complete set of expectations, click the link below.  Remember, all students will be required to evaluate the others' presentations.  You should preview the evaluation for to get further clues as to the means of assessment.

Oral presentation guidelines  -  Oral presentation evaluation form
Date
Presenters
Source Journal Presented Paper
March 5 Adam / Charlie
Chemistry and Biology link to paper
  Christine / Abigael
Biochemistry paper
March 7
Kayla / Rachel
ACS Chemical Biology paper
  Beatrice / Jackson
Molecular Cell paper
March 9  
Tyler
Nucleic Acids Research link to paper
   







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